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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PEX2 All Species: 26.36
Human Site: S289 Identified Species: 44.62
UniProt: P28328 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P28328 NP_000309.1 305 34843 S289 K C G T E V H S L Q P L K S G
Chimpanzee Pan troglodytes XP_519817 326 37490 S310 K C G T E V H S L Q P L K S G
Rhesus Macaque Macaca mulatta XP_001089931 253 28601 S237 K C G T E V H S L Q P L K S G
Dog Lupus familis XP_544136 305 35062 S289 K C G T E V Q S L Q P L K S G
Cat Felis silvestris
Mouse Mus musculus P55098 305 34713 S289 K C G T E V H S V Q P L K A G
Rat Rattus norvegicus P24392 305 34749 S289 K C G T E V H S V Q P L K S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519317 263 28547 R240 Q P G S G T Y R A L T V C A T
Chicken Gallus gallus NP_001008454 304 35215 S289 K C G S E V H S L Q P L K Y K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648210 281 32351 A256 Y C Y Y C L N A N V L T D A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202188 340 38906 C324 V C G E W P T C P Q E M G C Q
Poplar Tree Populus trichocarpa XP_002299722 341 39134 A326 R C G E A V V A M Q R H S S L
Maize Zea mays NP_001131851 337 38302 C321 S A T T S Y R C T R C D G A V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CA86 333 38156 F312 R C A S A A S F R C L R C N E
Baker's Yeast Sacchar. cerevisiae P32800 271 30733 V247 A N Y C Y V C V V K A L E W S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.6 80.9 89.8 N.A. 86.8 87.8 N.A. 28.5 73.7 N.A. N.A. N.A. 32.1 N.A. N.A. 33.2
Protein Similarity: 100 88.3 82.6 94.7 N.A. 94 94.7 N.A. 41.3 84.5 N.A. N.A. N.A. 48.5 N.A. N.A. 50.5
P-Site Identity: 100 100 100 93.3 N.A. 86.6 93.3 N.A. 6.6 80 N.A. N.A. N.A. 6.6 N.A. N.A. 20
P-Site Similarity: 100 100 100 93.3 N.A. 100 100 N.A. 40 86.6 N.A. N.A. N.A. 33.3 N.A. N.A. 26.6
Percent
Protein Identity: 28.4 27 N.A. 29.4 25.2 N.A.
Protein Similarity: 47.5 48 N.A. 50.7 40 N.A.
P-Site Identity: 33.3 6.6 N.A. 6.6 13.3 N.A.
P-Site Similarity: 53.3 20 N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 8 0 15 8 0 15 8 0 8 0 0 29 0 % A
% Cys: 0 79 0 8 8 0 8 15 0 8 8 0 15 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 8 8 0 0 % D
% Glu: 0 0 0 15 50 0 0 0 0 0 8 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 72 0 8 0 0 0 0 0 0 0 15 0 43 % G
% His: 0 0 0 0 0 0 43 0 0 0 0 8 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 50 0 0 0 0 0 0 0 0 8 0 0 50 0 8 % K
% Leu: 0 0 0 0 0 8 0 0 36 8 15 58 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % M
% Asn: 0 8 0 0 0 0 8 0 8 0 0 0 0 8 0 % N
% Pro: 0 8 0 0 0 8 0 0 8 0 50 0 0 0 0 % P
% Gln: 8 0 0 0 0 0 8 0 0 65 0 0 0 0 8 % Q
% Arg: 15 0 0 0 0 0 8 8 8 8 8 8 0 0 0 % R
% Ser: 8 0 0 22 8 0 8 50 0 0 0 0 8 43 15 % S
% Thr: 0 0 8 50 0 8 8 0 8 0 8 8 0 0 8 % T
% Val: 8 0 0 0 0 65 8 8 22 8 0 8 0 0 8 % V
% Trp: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % W
% Tyr: 8 0 15 8 8 8 8 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _